Our partner Test Facilities can provide the full range of toxicity studies to support the drug development in rodents and non-rodents (rabbits, dogs, minipigs, marmosets and NHP) according to the international regulatory requirements and animal welfare legislation.
General Toxicity
- Dose Range Finding and Maximum Tolerated Dose studies
- Single dose and preliminary TK
- Subacute (4wks), chronic studies up to 52 weeks including TK
- Long-term infusion studies
- Carcinogenicity studies with conventional strains and genetically modified animal models
- Local tolerability
- Phototoxicity
Reproductive Toxicity (Segments I, II, III)
- Fertility
- Embryo-foetal development
- Pre and post-natal development
- Multigeneration studies
Genetic Toxicity
- Complete range of in-vitro and in-vivo tests (Ames, chromosomal aberration, micronucleus)
Special Toxicity Studies and Services
- Irritation studies
- Sensitisation, allergenicity tests
- Local Lymph node assay (LLNA)
- Immunogenicity
- Customized toxicology studies
- Histopathology on contract and peer-review