Our partner Test Facilities can provide the full range of toxicity studies to support the drug development in rodents and non-rodents (rabbits, dogs, minipigs, marmosets and NHP) according to the international regulatory requirements and animal welfare legislation.

General Toxicity

  • Dose Range Finding and Maximum Tolerated Dose studies
  • Single dose and preliminary TK
  • Subacute (4wks), chronic studies up to 52 weeks including TK
  • Long-term infusion studies
  • Carcinogenicity studies with conventional strains and genetically modified animal models
  • Local tolerability
  • Phototoxicity

Reproductive Toxicity (Segments I, II, III)

  • Fertility
  • Embryo-foetal development
  • Pre and post-natal development
  • Multigeneration studies

Genetic Toxicity

  • Complete range of in-vitro and in-vivo tests (Ames, chromosomal aberration, micronucleus)

Special Toxicity Studies and Services

  • Irritation studies
  • Sensitisation, allergenicity tests
  • Local Lymph node assay (LLNA)
  • Immunogenicity
  • Customized toxicology studies
  • Histopathology on contract and peer-review