Pharmaceuticals – Imaging

In vivo Imaging Non-Clinical Services: a powerful tool in assistance/to the aid of your preclinical development

In vivo imaging refers to the use of all non-invasive or minimally invasive imaging techniques to visualize and analyze biological processes in living animal models, before clinical trials in humans. These techniques are extremely usefull to understand and quantify organ compound distribution and accumulation, evaluate drug efficacy and monitor treatment responses for different pathology models.

Longitudinal Imaging studies also helps to reduce use of animals, as it is possible to follow the behaviour and therapy response of each animal over the whole time study.

Cronet, whether you are developing a diagnostic, therapeutic, or a theragnostic agent can help you find the best in vivo imaging solution to point your research in the right direction in a faster and more cost-effective way.

Cronet, along with reliable partner laboratories, helps you prioritize the candidates in your pipeline by providing in vivo targeting and biodistribution data analysis that is crucial in the decision-making process to select the most likely successful candidates for clinical studies.

Such expertise and knowledge make Cronet a perfect business partner for companies whose first purpose is to identify lead molecules for future clinical trials, minimizing the chances of failure.

Why Imaging Non-Clinical Services are useful and necessary

In-vivo imaging enable to detrmine biodistribution quantification, drug organ accumulation at specific timepoints, funcional biological dose and toxicities/drug interactions to predict and optimize what will be needed in human.

Cronet holds a vast and experiential knowledge in the preclinical imaging field and can help you decide among the different imaging modalities which one best suits your scientific research:

Nuclear medicine, Positron Emission Tomography (PET/SPECT)
Computed tomography (CT)
Ultrasound and Photoacustic imaging (HFUS)
Bioluminescence/near-infrared imaging (NIR)
Magnetic Resonance Imaging (MRI)
Quantitative Whole-Body Autoradiography (QWBA)

Each imaging technique could be suitable to your scientific goal, but Cronet can advice, guide and assist you on the choice of the best one to succeed with your research.

Cronet has been working as strategical partner for several pharma and biotech companies to develop new diagnoistic/therapeutic/theranostic agents for bone/cartilage repairing, oncology and inflammation deseases/conditions. We have supported clients in the process of findings appropriate imaging CRO, supervising scientific studies, analyzing data and filing ad hoc reports for regulatory agencies.