General Pharmacology
More than 100 classical pharmacology validated assays are available for the evaluation of the pharmacological activity of candidate drugs.
Isolated Organs
- Isolated ileum Guinea pig
- Isolated duodenum
- Isolated trachea
- Isolated uterus
- Isolated vas deferens
- Isolated urethra
- Isolated trigone
- Isolated corpus cavernosum
- Isolated colon
- Isolated bladder
Renal Function
- Saline overload diuresis
- Streptozotocin induced renal failure in spontaneously hypertensive rats (SHR) ZDF rat (hyperinsulinaemic obese, renal failure)
- Glycerol induced acute renal failure
- L-NAME induced chronic renal failure
Gastrointestinal system
- Intestinal transit and gastric emptying
- Bilary secretion in anaesthetised animals
- Gastric emptying (liquids) – Gastric emptying (solids)
- Gastric secretion (SHAY method)
- Gastric ulcers protection following pyloric ligation
- Gastric ulcers induction potency
- Continuous gastric pH monitoring in conscious animals
- Healing promoting effect on subchronic gastric ulcers
- Gastric acid secretion (GHOSH and SCHILD method)
- Subacute lactose induced diarrhoea model
Immune System
- Dinitrofluorobenzene delayed hypersensitivity
- Immediate hypersensitivity test after acute or chronic exposure
- Direct hemolysis plaque forming cells
- Mouse ear swelling test
- Local lymph node assay
Blood
- Inhibition of platelet aggregation (ADP, collagen, arachidonic acid, thrombin, PAF, A23187) – ex vivo and in vivo
- Blood coagulation: clotting time, prothrombin time (PT), activated partial prothrombin time (APTT) and thrombin time (TT)
- Bleeding time in anaesthetised animals
- Venous thrombosis according to WESSLER (Xa factor, thromboplastin, thrombin)
- Arterial thrombosis induced by FeCl3