General Pharmacology

More than 100 classical pharmacology validated assays are available for the evaluation of the pharmacological activity of candidate drugs.

Isolated Organs

  • Isolated ileum Guinea pig
  • Isolated duodenum
  • Isolated trachea
  • Isolated uterus
  • Isolated vas deferens
  • Isolated urethra
  • Isolated trigone
  • Isolated corpus cavernosum
  • Isolated colon
  • Isolated bladder

Renal Function

  • Saline overload diuresis
  • Streptozotocin induced renal failure in spontaneously hypertensive rats (SHR) ZDF rat (hyperinsulinaemic obese, renal failure)
  • Glycerol induced acute renal failure
  • L-NAME induced chronic renal failure

Gastrointestinal system

  • Intestinal transit and gastric emptying
  • Bilary secretion in anaesthetised animals
  • Gastric emptying (liquids) – Gastric emptying (solids)
  • Gastric secretion (SHAY method)
  • Gastric ulcers protection following pyloric ligation
  • Gastric ulcers induction potency
  • Continuous gastric pH monitoring in conscious animals
  • Healing promoting effect on subchronic gastric ulcers
  • Gastric acid secretion (GHOSH and SCHILD method)
  • Subacute lactose induced diarrhoea model

Immune System

  • Dinitrofluorobenzene delayed hypersensitivity
  • Immediate hypersensitivity test after acute or chronic exposure
  • Direct hemolysis plaque forming cells
  • Mouse ear swelling test
  • Local lymph node assay


  • Inhibition of platelet aggregation (ADP, collagen, arachidonic acid, thrombin, PAF, A23187) – ex vivo and in vivo
  • Blood coagulation: clotting time, prothrombin time (PT), activated partial prothrombin time (APTT) and thrombin time (TT)
  • Bleeding time in anaesthetised animals
  • Venous thrombosis according to WESSLER (Xa factor, thromboplastin, thrombin)
  • Arterial thrombosis induced by FeCl3

Customized Pharmacology tests are set up according to Client’s need in in-vitro and in-vivo models.